STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
XRCC2DNA repair protein XRCC2. (322 aa)    
Predicted Functional Partners:
RAD51B
DNA repair protein RAD51 homolog 2 isoform X2.
   
0.994
RAD51C
DNA repair protein RAD51 homolog 3 isoform X2.
   
0.990
RAD51D
DNA repair protein RAD51 homolog 4 isoform X1.
   
 0.956
ENSPCTP00005031624
annotation not available
   
 0.956
XRCC3
DNA repair protein XRCC3 isoform X2.
   
 0.940
WRN
Werner syndrome ATP-dependent helicase isoform X1.
   
 0.916
DMC1
Meiotic recombination protein DMC1/LIM15 homolog; Belongs to the RecA family.
   
0.886
ENSPCTP00005016534
annotation not available
   
 0.792
RAD51
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
   
0.792
BRCA2
LOW QUALITY PROTEIN: breast cancer type 2 susceptibility protein.
    
 0.783
Your Current Organism:
Physeter catodon
NCBI taxonomy Id: 9755
Other names: P. catodon, Physeter macrocephalus, sperm whale
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.