STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFSEmbryonal Fyn-associated substrate-like. (561 aa)    
Predicted Functional Partners:
MYSM1
Histone H2A deubiquitinase MYSM1 isoform X1.
   
 0.768
ENSPCTP00005027245
Intersectin-2-like isoform X1.
     
 0.674
ITSN2
Intersectin-2 isoform X1.
     
 0.674
CRK
Adapter molecule crk isoform X1.
    
 0.652
CRKL
Crk-like protein.
    
 0.634
PTK2B
Protein-tyrosine kinase 2-beta isoform X3; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.614
PTK2
Focal adhesion kinase 1 isoform X10; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.614
RAPGEF1
Rap guanine nucleotide exchange factor 1.
    
 0.608
BCAR3
Breast cancer anti-estrogen resistance protein 3 isoform X2.
    
 0.605
DCTN2
Dynactin subunit 2 isoform X2.
   
 0.600
Your Current Organism:
Physeter catodon
NCBI taxonomy Id: 9755
Other names: P. catodon, Physeter macrocephalus, sperm whale
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.