STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDE6CPhosphodiesterase. (860 aa)    
Predicted Functional Partners:
GNAT2
LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(T) subunit alpha-2.
   
 0.950
GUK1
Guanylate kinase isoform X4.
   
 
 0.946
PDE6H
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma.
   
 
 0.917
GMPR2
GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
    
 0.909
CNGB3
LOW QUALITY PROTEIN: cyclic nucleotide-gated cation channel beta-3.
   
 0.901
GMPS
GMP synthase [glutamine-hydrolyzing].
     
 0.900
APRT
Adenine phosphoribosyltransferase isoform X2.
     
 0.900
PDE6G
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma.
   
 0.832
GUCY2D
Guanylate cyclase.
   
 0.821
GUCY2F
Guanylate cyclase.
   
 0.821
Your Current Organism:
Physeter catodon
NCBI taxonomy Id: 9755
Other names: P. catodon, Physeter macrocephalus, sperm whale
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