Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PPP6R2Protein phosphatase 6 regulatory subunit 2. (915 aa)    
Predicted Functional Partners:
PPP6C
Serine/threonine-protein phosphatase.
   
 0.960
ANKRD28
Ankyrin repeat domain 28.
   
 0.772
ANKRD44
Ankyrin repeat domain 44.
   
 0.772
ANKRD52
Ankyrin repeat domain 52.
    
 0.764
PPP6R1
Protein phosphatase 6 regulatory subunit 1.
   
 
 0.714
USP10
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
   
   0.677
PLK1
Serine/threonine-protein kinase PLK.
    
 
 0.673
DYM
Dymeclin.
   
  
 0.592
CTDSP2
CTD small phosphatase 2.
      
 0.570
SH3GL3
SH3 domain containing GRB2 like 3, endophilin A3.
      
 0.567
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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