Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KLF10Kruppel like factor 10. (480 aa)    
Predicted Functional Partners:
FOXP3
Forkhead box P3.
    
 0.818
NAB2
NGFI-A binding protein 2.
    
 0.701
SP1
Sp1 transcription factor.
    
 0.597
SIAH1
E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
    
 
 0.552
TBRG1
Transforming growth factor beta regulator 1.
    
 0.521
TGFB1
Transforming growth factor beta; Belongs to the TGF-beta family.
    
 
 0.515
SIN3B
SIN3 transcription regulator family member B.
    
 0.506
SIN3A
SIN3 transcription regulator family member A.
    
 0.506
ELL2
Elongation factor for RNA polymerase II 2.
    
 
 0.480
NR1I2
Nuclear receptor subfamily 1 group I member 2.
    
 0.444
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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