Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRICKLE2Prickle planar cell polarity protein 2. (857 aa)    
Predicted Functional Partners:
VANGL1
Vang-like protein.
    
 0.977
VANGL2
Vang-like protein.
    
 0.970
DVL1
Dishevelled segment polarity protein 1.
    
 0.965
DVL3
Dishevelled segment polarity protein 3.
    
 0.922
PRICKLE1
Prickle planar cell polarity protein 1.
    
 0.892
DVL2
Dishevelled segment polarity protein 2.
    
 0.890
PRICKLE4
Uncharacterized protein.
    
 0.887
PRICKLE3
Prickle planar cell polarity protein 3.
     
  0.846
INVS
Inversin.
   
 0.724
FZD3
Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.647
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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