STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERMP1Endoplasmic reticulum metallopeptidase 1. (799 aa)    
Predicted Functional Partners:
TASP1
Taspase 1.
   
  
 0.630
ERH
Enhancer of rudimentary homolog; May have a role in the cell cycle.
 
      0.590
ATAD1
ATPase family AAA domain containing 1; Belongs to the AAA ATPase family.
     
 0.571
UPP1
Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
   
  
 0.564
TMTC2
Transmembrane O-mannosyltransferase targeting cadherins 2.
    
 0.539
WDR81
WD repeat domain 81.
   
 
 0.532
EPOR
Erythropoietin receptor.
    
 0.531
RIC1
RIC1 homolog, RAB6A GEF complex partner 1.
      
 0.527
ATP6AP2
ATPase H+ transporting accessory protein 2.
    
 
 0.459
TES
Testin; Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor (By similarity); Belongs to the prickle / espinas / testin family.
    
 
 0.458
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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