Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ERC1ELKS/RAB6-interacting/CAST family member 1. (1074 aa)    
Predicted Functional Partners:
ERC2
Uncharacterized protein.
   
 
 0.919
G3UEY1_LOXAF
Uncharacterized protein.
   
 
 0.919
PHLDB2
Pleckstrin homology like domain family B member 2.
    
 
 0.897
RIMS2
Regulating synaptic membrane exocytosis 2.
   
 
 0.839
G3UF18_LOXAF
C2 domain-containing protein.
   
 
 0.839
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
    
 0.764
RAB6B
RAB6B, member RAS oncogene family.
    
 
 0.732
KIAA0930
KIAA0930.
    
 
 0.716
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
    
 0.679
G3T030_LOXAF
Uncharacterized protein.
   
 
 0.661
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (26%) [HD]