Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NDRG4NDRG family member 4. (404 aa)    
Predicted Functional Partners:
NDRG1
N-myc downstream regulated 1.
    
   0.665
BMP3
Bone morphogenetic protein 3; Belongs to the TGF-beta family.
      
 0.615
TYW5
tRNA-yW synthesizing protein 5.
      
 0.568
ENKUR
Enkurin, TRPC channel interacting protein.
      
 0.534
IP6K3
Kinase; Belongs to the inositol phosphokinase (IPK) family.
      
 0.533
DNAJB11
J domain-containing protein.
   
 
 0.508
CRIP2
Cysteine rich protein 2.
   
  
 0.500
TANC2
Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2.
   
 
 0.475
SEPTIN9
Septin 9; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
   
  
 0.473
RNF31
Uncharacterized protein.
      
 0.467
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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