STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CLN3Battenin. (436 aa)    
Predicted Functional Partners:
HMGCL
3-hydroxy-3-methylglutaryl-CoA lyase.
 
      0.879
HMGCLL1
3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1.
 
      0.866
CLN5
Uncharacterized protein.
    
 
 0.840
PPT1
Palmitoyl-protein thioesterase 1.
    
 
 0.835
CLN6
CLN6 transmembrane ER protein.
   
  
 0.827
CLN8
TLC domain-containing protein.
      
 0.808
TPP1
Tripeptidyl peptidase 1.
      
 0.800
MFSD8
Major facilitator superfamily domain containing 8.
   
 
 0.743
AUP1
AUP1 lipid droplet regulating VLDL assembly factor.
    
 
 0.666
RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]
    
   0.665
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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