STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DEFB124Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (70 aa)    
Predicted Functional Partners:
G3TM46_LOXAF
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.696
DEFB135
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.682
DEFB113
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.628
DEFB128
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.622
DEFB123
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.558
G3U4L4_LOXAF
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.558
PROZ
Protein Z, vitamin K dependent plasma glycoprotein; Belongs to the peptidase S1 family.
      
 0.526
CHST13
Carbohydrate sulfotransferase.
      
 0.521
DEFB136
Uncharacterized protein.
     
 0.520
GNG10
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
      
 0.518
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.