STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (298 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
   
 0.808
G3U095_LOXAF
Uncharacterized protein.
   
 0.808
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
    
 0.782
GRB2
Growth factor receptor bound protein 2.
   
 0.778
AFDN
Afadin, adherens junction formation factor.
    
 
 0.768
ZHX2
Zinc fingers and homeoboxes 2.
   
 0.766
FRMPD2
FERM and PDZ domain containing 2.
    
 0.743
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
    
 0.739
G3BP1
G3BP stress granule assembly factor 1.
    
 
 0.728
MDK
Midkine.
      
 0.696
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.