STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DCSTAMPDendrocyte expressed seven transmembrane protein. (462 aa)    
Predicted Functional Partners:
NFATC1
Nuclear factor of activated T cells 1.
      
 0.749
TNFSF11
Tumor necrosis factor ligand 6B; Belongs to the tumor necrosis factor family.
  
   
 0.598
OCSTAMP
Osteoclast stimulatory transmembrane protein.
      
 0.583
CREB3
cAMP responsive element binding protein 3.
    
 0.575
CSF1
Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...]
      
 0.548
CTSK
Cathepsin K; Belongs to the peptidase C1 family.
      
 0.543
CD47
CD47 molecule.
      
 0.441
ACP5
Tartrate-resistant acid phosphatase type 5.
      
 0.441
OSCAR
Osteoclast associated Ig-like receptor.
      
 0.440
B3GNT4
Hexosyltransferase.
      
 0.438
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.