STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEA1Early endosome antigen 1. (1414 aa)    
Predicted Functional Partners:
RAB5A
RAB5A, member RAS oncogene family.
    
 0.855
RAB5B
RAB5B, member RAS oncogene family.
    
 0.855
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
      
 0.725
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
      
 0.725
TFRC
Transferrin receptor.
      
 0.723
LAMP1
Lysosomal associated membrane protein 1.
      
 0.723
CD63
Tetraspanin.
      
 0.723
LAMP2
Lysosomal associated membrane protein 2.
      
 0.723
SNX1
Sorting nexin 1.
      
 0.718
CANX
Calnexin.
    
 
 0.706
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.