STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LDLRAP1Low density lipoprotein receptor adaptor protein 1. (281 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
    
 0.949
G3U095_LOXAF
Uncharacterized protein.
    
 0.949
AP2B1
AP complex subunit beta.
    
 0.918
LDLR
Low density lipoprotein receptor.
    
 0.912
LRP2
LDL receptor related protein 2.
    
 0.843
AP1B1
AP complex subunit beta.
    
 0.765
APOB
Apolipoprotein B.
     
 0.759
LRP4
LDL receptor related protein 4.
    
 0.717
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
    
 
 0.678
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
    
 
 0.678
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.