STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NRDCNardilysin convertase. (1222 aa)    
Predicted Functional Partners:
IDE
Insulin degrading enzyme; Belongs to the peptidase M16 family.
   
 
 0.825
TREH
Trehalase.
   
  
 0.805
DNPEP
Aspartyl aminopeptidase; Belongs to the peptidase M18 family.
   
  
 0.792
OXNAD1
Oxidoreductase NAD binding domain containing 1.
      
 0.737
INS
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
    
 0.735
UBA52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
  0.611
GPATCH11
G-patch domain containing 11.
    
 
 0.605
CCDC130
Coiled-coil domain containing 130.
      
 0.601
RPS27A
Ubiquitin-like domain-containing protein.
    
  0.599
G3U9C8_LOXAF
Ubiquitin-like domain-containing protein.
    
  0.599
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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