STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SUDS3SDS3 homolog, SIN3A corepressor complex component. (329 aa)    
Predicted Functional Partners:
SAP30
Sin3A associated protein 30.
   
 0.992
ARID4B
AT-rich interaction domain 4B.
   
 0.986
ARID4A
AT-rich interaction domain 4A.
   
 0.974
SAP18
Histone deacetylase complex subunit SAP18; Component of the SIN3-repressing complex. Enhances the ability of SIN3-HDAC1-mediated transcriptional repression. When tethered to the promoter, it can direct the formation of a repressive complex to core histone proteins. Auxiliary component of the splicing- dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or durin [...]
    
 0.952
ING2
Inhibitor of growth protein.
   
 
 0.942
SAP30L
SAP30 like.
   
 0.929
SAP130
Sin3A associated protein 130.
   
 0.920
RBBP4
RB binding protein 4, chromatin remodeling factor.
    
 0.914
RBBP7
RB binding protein 7, chromatin remodeling factor.
    
 0.914
SIN3B
SIN3 transcription regulator family member B.
   
 0.873
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.