STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SUDS3SDS3 homolog, SIN3A corepressor complex component. (329 aa)    
Predicted Functional Partners:
ARID4B
AT-rich interaction domain 4B.
   
 0.991
ARID4A
AT-rich interaction domain 4A.
   
 0.988
SAP18
Histone deacetylase complex subunit SAP18; Component of the SIN3-repressing complex. Enhances the ability of SIN3-HDAC1-mediated transcriptional repression. When tethered to the promoter, it can direct the formation of a repressive complex to core histone proteins. Auxiliary component of the splicing- dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or durin [...]
     
 0.981
ING1
Inhibitor of growth protein.
    
 
 0.950
SAP30
Sin3A associated protein 30.
   
 0.945
SIN3B
SIN3 transcription regulator family member B.
   
 0.909
SIN3A
SIN3 transcription regulator family member A.
   
 0.909
RBBP4
RB binding protein 4, chromatin remodeling factor.
    
 0.879
RBBP7
RB binding protein 7, chromatin remodeling factor.
    
 0.879
SAP30L
SAP30 like.
   
 0.842
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.