STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NAPSANapsin A aspartic peptidase; Belongs to the peptidase A1 family. (370 aa)    
Predicted Functional Partners:
CTSH
Cathepsin H; Belongs to the peptidase C1 family.
   
 0.693
SFTPB
Surfactant protein B.
   
 0.652
AGT
Angiotensinogen; Belongs to the serpin family.
   
 0.566
CTSB
Cathepsin B; Belongs to the peptidase C1 family.
   
 0.535
NCLN
Nicalin.
      
 0.530
KRT7
Keratin 7; Belongs to the intermediate filament family.
      
 0.522
LAMP1
Lysosomal associated membrane protein 1.
   
 
 0.489
ATP6AP2
ATPase H+ transporting accessory protein 2.
   
 0.472
HBB/D
Hemoglobin subunit delta; Belongs to the globin family.
    
 0.461
INS
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
 0.445
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.