STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KPNB1Karyopherin subunit beta 1. (873 aa)    
Predicted Functional Partners:
RAN
GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.
   
 0.981
KPNA1
Importin subunit alpha; Functions in nuclear protein import.
   
 0.970
RANBP2
RAN binding protein 2.
   
 0.957
ADGRD1
Adhesion G protein-coupled receptor D1; Belongs to the G-protein coupled receptor 2 family.
   
 0.954
NUP153
Nucleoporin 153.
   
 0.948
NUP98
Nucleoporin 98.
   
 0.934
KPNA2
Importin subunit alpha; Functions in nuclear protein import.
   
 0.931
SNUPN
Snurportin-1; Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs. Belongs to the snurportin family.
    
 0.914
DKC1
Dyskerin pseudouridine synthase 1.
    
 
 0.912
SREBF2
Sterol regulatory element binding transcription factor 2.
    
 0.911
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.