STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GPC5Glypican 5; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (468 aa)    
Predicted Functional Partners:
CHEK2
Checkpoint kinase 2.
      
 0.659
PNPT1
Polyribonucleotide nucleotidyltransferase 1.
      
 0.639
NOTUM
Notum, palmitoleoyl-protein carboxylesterase.
    
 0.611
DHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.570
UNC5D
Unc-5 netrin receptor D.
    
 
 0.563
APOE
Apolipoprotein E.
     
 0.510
IHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.502
SHH
Sonic hedgehog signaling molecule.
    
 0.502
SDC3
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
     
 0.486
SDC2
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
    
 0.478
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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