Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ATAD1ATPase family AAA domain containing 1; Belongs to the AAA ATPase family. (361 aa)    
Predicted Functional Partners:
PEX19
Uncharacterized protein.
    
 0.877
GET3
ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]
  
 
 0.843
GDAP1
Ganglioside induced differentiation associated protein 1; Belongs to the GST superfamily.
     
 0.842
PEX12
Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family.
    
 0.840
PEX13
Peroxisomal biogenesis factor 13.
   
 0.742
PEX16
Peroxisomal membrane protein PEX16.
     
 0.739
PEX14
Peroxisomal biogenesis factor 14.
    
 0.738
PXMP4
Peroxisomal membrane protein 4; Belongs to the peroxisomal membrane protein PXMP2/4 family.
   
 
 0.720
ABCD3
ATP binding cassette subfamily D member 3.
   
 
 0.713
PEX3
Peroxisomal biogenesis factor 3.
    
 0.702
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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