STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IRF6Interferon regulatory factor 6. (474 aa)    
Predicted Functional Partners:
DSCC1
DNA replication and sister chromatid cohesion 1.
   
 
 0.583
RAD51D
DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents; Belongs to the RecA family. RAD51 subfamily.
      
 0.578
AP3B2
AP-3 complex subunit beta.
    
 
 0.574
RAB3GAP2
RAB3 GTPase activating non-catalytic protein subunit 2.
      
 0.573
MKX
Mohawk homeobox.
    
 
 0.571
ATRX
ATRX chromatin remodeler.
    
 0.562
MYD88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.545
PRRG4
Proline rich and Gla domain 4.
      
 0.525
RIPK4
Receptor interacting serine/threonine kinase 4.
   
 0.523
BTBD1
BTB domain containing 1.
      
 0.520
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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