Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MAP2K5Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (446 aa)    
Predicted Functional Partners:
MAP3K3
Mitogen-activated protein kinase kinase kinase 3.
    
 0.991
MAPK7
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
 0.987
MAP3K2
Mitogen-activated protein kinase kinase kinase 2.
    
 0.980
MAPK1
Mitogen-activated protein kinase.
   
 0.879
MAPK3
Mitogen-activated protein kinase.
   
 0.879
SQSTM1
Sequestosome 1.
    
 
 0.803
MAP3K4
Mitogen-activated protein kinase kinase kinase 4.
    
 0.771
SKOR1
SKI family transcriptional corepressor 1.
 
    
 0.764
KSR2
Kinase suppressor of ras 2.
   
 0.740
KSR1
Kinase suppressor of ras 1.
   
 0.740
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.