STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAP2K5Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (446 aa)    
Predicted Functional Partners:
MAPK7
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
0.994
MAP3K3
Mitogen-activated protein kinase kinase kinase 3.
  
0.993
MAP3K2
Mitogen-activated protein kinase kinase kinase 2.
  
0.990
KSR2
Kinase suppressor of ras 2.
   
 0.761
KSR1
Kinase suppressor of ras 1.
   
 0.761
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
   
0.731
ARAF
A-Raf proto-oncogene, serine/threonine kinase.
   
0.731
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
   
0.731
MAPK1
Mitogen-activated protein kinase.
   
0.726
MAPK3
Mitogen-activated protein kinase.
   
0.726
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.