STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ESYT2Extended synaptotagmin 2. (845 aa)    
Predicted Functional Partners:
ESYT1
Extended synaptotagmin 1.
   
  0.991
ESYT3
Extended synaptotagmin 3.
    
  0.933
UBE2V1
UBIQUITIN_CONJUGAT_2 domain-containing protein.
     
  0.775
DERL1
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
    
 
 0.768
NCAPG2
Non-SMC condensin II complex subunit G2.
 
    
 0.737
WDR60
WD repeat domain 60.
      
 0.720
MBLAC2
Metallo-beta-lactamase domain containing 2.
      
 0.686
OSBPL8
Oxysterol-binding protein; Belongs to the OSBP family.
   
 
 0.642
OSBP
Oxysterol-binding protein; Belongs to the OSBP family.
   
 
 0.607
KIAA2013
KIAA2013.
      
 0.562
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.