STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
OAZ2Ornithine decarboxylase antizyme 2. (185 aa)    
Predicted Functional Partners:
AZIN1
Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
    
 0.986
ODC1
Ornithine decarboxylase 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
    
 0.968
AZIN2
Antizyme inhibitor 2; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
    
 0.900
PIF1
ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...]
      
 0.675
IGSF8
Immunoglobulin superfamily member 8.
      
 0.655
PSMA3
Proteasome subunit alpha type.
   
 
 0.580
ADAR
Adenosine deaminase RNA specific.
      
 0.569
OAZ1
Ornithine decarboxylase antizyme 1.
     
  0.566
ATG16L2
Autophagy related 16 like 2.
      
 0.554
RBPMS2
RNA binding protein, mRNA processing factor 2.
 
    
 0.539
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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