STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SGPP2Sphingosine-1-phosphate phosphatase 2. (354 aa)    
Predicted Functional Partners:
SGPL1
Sphingosine-1-phosphate lyase 1.
    
 0.957
CERS5
Ceramide synthase 5.
   
 0.905
CERS3
Ceramide synthase 3.
   
 0.899
ASAH1
N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family.
    
 0.895
PLPP1
Phospholipid phosphatase 1.
     
 0.895
SPHK1
Sphingosine kinase 1.
  
 0.890
DEGS1
Delta 4-desaturase, sphingolipid 1.
     
 0.889
SMPD2
Sphingomyelin phosphodiesterase 2.
     
 0.882
ACER2
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
     
 0.880
UGCG
UDP-glucose ceramide glucosyltransferase.
    
 0.878
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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