Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IGSF11Immunoglobulin superfamily member 11. (420 aa)    
Predicted Functional Partners:
G3TEN6_LOXAF
Ig-like domain-containing protein.
     
 0.906
IGSF21
Immunoglobin superfamily member 21.
  
   
 0.586
GJA5
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.580
LRFN2
Leucine rich repeat and fibronectin type III domain containing 2.
      
 0.578
IGSF9
Immunoglobulin superfamily member 9.
   
  
 0.578
KITLG
Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family.
      
 0.560
IGSF6
Immunoglobulin superfamily member 6.
  
   
 0.556
IGSF5
Uncharacterized protein.
      
 0.547
WFIKKN2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2.
  
     0.521
PPP1R36
Protein phosphatase 1 regulatory subunit 36.
      
 0.520
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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