STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCNE2Cyclin E2; Belongs to the cyclin family. (404 aa)    
Predicted Functional Partners:
CDK2
Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.
   
 0.995
CDKN1A
Cyclin dependent kinase inhibitor 1A.
   
 0.992
CDKN1B
Cyclin dependent kinase inhibitor 1B.
   
 0.983
RB1
RB transcriptional corepressor 1.
   
 0.977
CDK4
Cyclin dependent kinase 4; Belongs to the protein kinase superfamily.
   
 0.975
RBL2
RB transcriptional corepressor like 2.
   
 0.974
RBL1
RB transcriptional corepressor like 1.
   
 0.974
SKP2
S-phase kinase associated protein 2.
   
 0.970
CUL1
Cullin 1; Belongs to the cullin family.
    
 0.969
CDC25A
Cell division cycle 25A.
   
 0.967
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.