STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HPGD15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (265 aa)    
Predicted Functional Partners:
PTGR1
Prostaglandin reductase 1.
   
 0.947
PTGES3
CS domain-containing protein.
     
 0.941
PTGES
Prostaglandin E synthase.
     
 0.929
PTGR2
Uncharacterized protein.
   
 0.929
PTGES2
Prostaglandin E synthase 2; Belongs to the GST superfamily.
     
 0.907
PRXL2B
Peroxiredoxin like 2B.
     
 0.896
ZADH2
Zinc binding alcohol dehydrogenase domain containing 2.
   
 0.876
FITM1
Fat storage inducing transmembrane protein 1.
      
 0.843
LOC100666118
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
 0.835
MGST1
Microsomal glutathione S-transferase 1.
     
 0.811
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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