STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HPGD15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (265 aa)    
Predicted Functional Partners:
FITM1
Fat storage inducing transmembrane protein 1.
      
 0.757
SLCO2A1
Solute carrier organic anion transporter family member.
   
  
 0.688
FABP3
Fatty acid binding protein 3; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
   
 
 0.643
CILP2
Cartilage intermediate layer protein 2.
      
 0.615
ERLIN2
ER lipid raft associated 2.
   
 
 0.601
PTGES3
CS domain-containing protein.
   
 
 0.525
HSD11B1
Hydroxysteroid 11-beta dehydrogenase 1.
  
  
 0.522
RSPO4
R-spondin 4.
   
 
 0.500
HSD17B1
Hydroxysteroid 17-beta dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
 0.485
RDH5
Retinol dehydrogenase 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
 0.478
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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