Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
TP53INP1Tumor protein p53 inducible nuclear protein 1. (241 aa)    
Predicted Functional Partners:
VMP1
Vacuole membrane protein 1.
     
 0.804
MAP1LC3B
Uncharacterized protein.
    
 0.730
MAP1LC3A
Microtubule associated protein 1 light chain 3 alpha.
    
 0.730
GABARAP
GABA type A receptor-associated protein.
    
 0.660
GABARAPL1
GABA type A receptor associated protein like 1.
    
 0.660
G3TQR5_LOXAF
Uncharacterized protein.
    
 0.660
GABARAPL2
GABA type A receptor associated protein like 2.
    
 0.637
G3TFZ3_LOXAF
Uncharacterized protein.
    
 0.591
G3UE69_LOXAF
Uncharacterized protein.
    
 0.591
TP53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.576
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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