STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ME2Malic enzyme. (584 aa)    
Predicted Functional Partners:
PC
Pyruvate carboxylase.
   
 0.935
FH
Fumarate hydratase.
  
 
 0.929
MDH1
Malate dehydrogenase.
  
 0.920
MDH2
Malate dehydrogenase.
  
 0.919
CS
Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.917
PKLR
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.907
PDHB
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 
 0.905
AGXT
Serine--pyruvate aminotransferase.
   
 
 0.898
LDHB
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.895
LDHD
Lactate dehydrogenase D.
  
 
 0.888
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.