STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SESN3Sestrin 3. (493 aa)    
Predicted Functional Partners:
SESN2
Sestrin 2.
  
  
0.942
SESN1
Sestrin 1.
  
  
0.921
DEPDC5
DEP domain-containing protein.
    
 0.819
PRKAA2
Non-specific serine/threonine protein kinase.
     
 0.806
WDR24
WD repeat domain 24.
    
 0.805
PRKAB1
Protein kinase AMP-activated non-catalytic subunit beta 1.
     
 0.798
PRKAG3
Protein kinase AMP-activated non-catalytic subunit gamma 3.
   
 
 0.792
PRKAA1
Non-specific serine/threonine protein kinase.
     
 0.792
PRKAB2
Protein kinase AMP-activated non-catalytic subunit beta 2.
     
 0.787
PRKAG1
Protein kinase AMP-activated non-catalytic subunit gamma 1.
   
 
 0.781
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.