| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BOP1 | TRMT11 | ENSLAFP00000000575 | ENSLAFP00000002841 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | tRNA methyltransferase 11 homolog. | 0.461 |
| BOP1 | TRMT2B | ENSLAFP00000000575 | ENSLAFP00000001289 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | tRNA methyltransferase 2 homolog B; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | 0.797 |
| DUS1L | OSGEP | ENSLAFP00000002687 | ENSLAFP00000003115 | Dihydrouridine synthase 1 like. | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | 0.620 |
| DUS1L | TRIT1 | ENSLAFP00000002687 | ENSLAFP00000014150 | Dihydrouridine synthase 1 like. | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family. | 0.589 |
| DUS1L | TRMT10A | ENSLAFP00000002687 | ENSLAFP00000018440 | Dihydrouridine synthase 1 like. | tRNA methyltransferase 10A. | 0.596 |
| DUS1L | TRMT11 | ENSLAFP00000002687 | ENSLAFP00000002841 | Dihydrouridine synthase 1 like. | tRNA methyltransferase 11 homolog. | 0.856 |
| DUS1L | TRMT12 | ENSLAFP00000002687 | ENSLAFP00000010465 | Dihydrouridine synthase 1 like. | tRNA methyltransferase 12 homolog. | 0.820 |
| DUS1L | TRMT2B | ENSLAFP00000002687 | ENSLAFP00000001289 | Dihydrouridine synthase 1 like. | tRNA methyltransferase 2 homolog B; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | 0.858 |
| DUS1L | TRMT5 | ENSLAFP00000002687 | ENSLAFP00000003018 | Dihydrouridine synthase 1 like. | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | 0.654 |
| DUS1L | TRMU | ENSLAFP00000002687 | ENSLAFP00000004293 | Dihydrouridine synthase 1 like. | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase. | 0.609 |
| DUS1L | YRDC | ENSLAFP00000002687 | ENSLAFP00000014721 | Dihydrouridine synthase 1 like. | YrdC N6-threonylcarbamoyltransferase domain containing. | 0.660 |
| OSGEP | DUS1L | ENSLAFP00000003115 | ENSLAFP00000002687 | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | Dihydrouridine synthase 1 like. | 0.620 |
| OSGEP | TRIT1 | ENSLAFP00000003115 | ENSLAFP00000014150 | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family. | 0.577 |
| OSGEP | TRMT10A | ENSLAFP00000003115 | ENSLAFP00000018440 | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | tRNA methyltransferase 10A. | 0.562 |
| OSGEP | TRMT11 | ENSLAFP00000003115 | ENSLAFP00000002841 | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | tRNA methyltransferase 11 homolog. | 0.580 |
| OSGEP | TRMT12 | ENSLAFP00000003115 | ENSLAFP00000010465 | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | tRNA methyltransferase 12 homolog. | 0.734 |
| OSGEP | TRMT2B | ENSLAFP00000003115 | ENSLAFP00000001289 | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | tRNA methyltransferase 2 homolog B; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | 0.760 |
| OSGEP | TRMT5 | ENSLAFP00000003115 | ENSLAFP00000003018 | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | 0.566 |
| OSGEP | TRMU | ENSLAFP00000003115 | ENSLAFP00000004293 | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase. | 0.577 |
| OSGEP | YRDC | ENSLAFP00000003115 | ENSLAFP00000014721 | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | YrdC N6-threonylcarbamoyltransferase domain containing. | 0.832 |
