STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TEPSINTEPSIN adaptor related protein complex 4 accessory protein. (595 aa)    
Predicted Functional Partners:
LRRC73
Leucine rich repeat containing 73.
      
 0.650
AP4S1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 
 0.643
AP4E1
Adaptor related protein complex 4 subunit epsilon 1.
    
 
 0.589
VSIG10
V-set and immunoglobulin domain containing 10.
   
  
 0.578
AP4B1
AP complex subunit beta; Belongs to the adaptor complexes large subunit family.
    
 
 0.570
NPRL2
NPR2 like, GATOR1 complex subunit.
      
 0.560
POLR3H
RNA polymerase III subunit H.
      
 0.551
AP4M1
AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...]
    
 
 0.545
GPAA1
Glycosylphosphatidylinositol anchor attachment 1.
      
 0.521
AARS1
Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family.
      
 0.517
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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