STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
TEPSINTEPSIN adaptor related protein complex 4 accessory protein. (595 aa)    
Predicted Functional Partners:
AP4S1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
   
 
 0.926
AP4B1
AP complex subunit beta; Belongs to the adaptor complexes large subunit family.
   
 
 0.923
AP4M1
AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...]
   
 
 0.896
AP4E1
Adaptor related protein complex 4 subunit epsilon 1.
   
 
 0.885
RUSC2
RUN and SH3 domain containing 2.
      
 0.829
RUSC1
RUN and SH3 domain containing 1.
      
 0.826
DAGLB
Lipase_3 domain-containing protein.
      
 0.804
LRRC73
Leucine rich repeat containing 73.
      
 0.766
ATG9A
Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.
      
 0.721
GPAA1
Glycosylphosphatidylinositol anchor attachment 1.
      
 0.662
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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