STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (746 aa)    
Predicted Functional Partners:
SUZ12
SUZ12 polycomb repressive complex 2 subunit.
   
 0.999
EED
Embryonic ectoderm development.
   
 0.998
EZH1
Enhancer of zeste 1 polycomb repressive complex 2 subunit.
  
 
0.997
AEBP2
AE binding protein 2.
   
 0.990
JARID2
Jumonji and AT-rich interaction domain containing 2.
   
 0.987
DNMT1
DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
   
 0.984
MTF2
Metal response element binding transcription factor 2.
   
 0.984
PHF19
PHD finger protein 19.
   
 0.982
PHF1
PHD finger protein 1.
   
 0.977
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.962
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.