| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DDIT3 | EIF2AK3 | ENSLAFP00000024019 | ENSLAFP00000017586 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] | Eukaryotic translation initiation factor 2 alpha kinase 3. | 0.623 |
| DDIT3 | NFE2 | ENSLAFP00000024019 | ENSLAFP00000001318 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] | Nuclear factor, erythroid 2. | 0.835 |
| DDIT3 | NFE2L1 | ENSLAFP00000024019 | ENSLAFP00000015526 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] | Nuclear factor, erythroid 2 like 1. | 0.574 |
| DDIT3 | NFE2L2 | ENSLAFP00000024019 | ENSLAFP00000013652 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] | Nuclear factor, erythroid 2 like 2. | 0.914 |
| DDIT3 | NFE2L3 | ENSLAFP00000024019 | ENSLAFP00000005792 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] | Nuclear factor, erythroid 2 like 3. | 0.574 |
| EIF2AK3 | DDIT3 | ENSLAFP00000017586 | ENSLAFP00000024019 | Eukaryotic translation initiation factor 2 alpha kinase 3. | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] | 0.623 |
| EIF2AK3 | NFE2 | ENSLAFP00000017586 | ENSLAFP00000001318 | Eukaryotic translation initiation factor 2 alpha kinase 3. | Nuclear factor, erythroid 2. | 0.852 |
| EIF2AK3 | NFE2L1 | ENSLAFP00000017586 | ENSLAFP00000015526 | Eukaryotic translation initiation factor 2 alpha kinase 3. | Nuclear factor, erythroid 2 like 1. | 0.631 |
| EIF2AK3 | NFE2L2 | ENSLAFP00000017586 | ENSLAFP00000013652 | Eukaryotic translation initiation factor 2 alpha kinase 3. | Nuclear factor, erythroid 2 like 2. | 0.928 |
| EIF2AK3 | NFE2L3 | ENSLAFP00000017586 | ENSLAFP00000005792 | Eukaryotic translation initiation factor 2 alpha kinase 3. | Nuclear factor, erythroid 2 like 3. | 0.631 |
| HMOX1 | KEAP1 | ENSLAFP00000024949 | ENSLAFP00000015010 | Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. | Kelch like ECH associated protein 1. | 0.807 |
| HMOX1 | MAFK | ENSLAFP00000024949 | ENSLAFP00000023485 | Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. | MAF bZIP transcription factor K. | 0.542 |
| HMOX1 | NFE2 | ENSLAFP00000024949 | ENSLAFP00000001318 | Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. | Nuclear factor, erythroid 2. | 0.739 |
| HMOX1 | NFE2L1 | ENSLAFP00000024949 | ENSLAFP00000015526 | Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. | Nuclear factor, erythroid 2 like 1. | 0.416 |
| HMOX1 | NFE2L2 | ENSLAFP00000024949 | ENSLAFP00000013652 | Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. | Nuclear factor, erythroid 2 like 2. | 0.960 |
| HMOX1 | NFE2L3 | ENSLAFP00000024949 | ENSLAFP00000005792 | Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. | Nuclear factor, erythroid 2 like 3. | 0.416 |
| KEAP1 | HMOX1 | ENSLAFP00000015010 | ENSLAFP00000024949 | Kelch like ECH associated protein 1. | Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. | 0.807 |
| KEAP1 | MAFK | ENSLAFP00000015010 | ENSLAFP00000023485 | Kelch like ECH associated protein 1. | MAF bZIP transcription factor K. | 0.431 |
| KEAP1 | NFE2 | ENSLAFP00000015010 | ENSLAFP00000001318 | Kelch like ECH associated protein 1. | Nuclear factor, erythroid 2. | 0.763 |
| KEAP1 | NFE2L1 | ENSLAFP00000015010 | ENSLAFP00000015526 | Kelch like ECH associated protein 1. | Nuclear factor, erythroid 2 like 1. | 0.952 |
