HDDC2 protein (Loxodonta africana) - STRING interaction network

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HDDC2

HD domain containing 2. (198 aa)

Predicted Functional Partners:

AK2

0.917

DUT

0.889

AK4

0.889

NT5E

0.886

PNP

0.882

TYMS

0.879

DGUOK

0.877

ASMTL

0.876

CDA

0.875

DTYMK

0.875

Your Current Organism:

Loxodonta africana

NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AK2	AK4	ENSLAFP00000004402	ENSLAFP00000006788	Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.	Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity.	0.871
AK2	ASMTL	ENSLAFP00000004402	ENSLAFP00000025438	Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.	Acetylserotonin O-methyltransferase like.	0.730
AK2	DGUOK	ENSLAFP00000004402	ENSLAFP00000016952	Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.	Deoxyguanosine kinase.	0.814
AK2	DTYMK	ENSLAFP00000004402	ENSLAFP00000015861	Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.	Deoxythymidylate kinase.	0.544
AK2	DUT	ENSLAFP00000004402	ENSLAFP00000004160	Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.	Deoxyuridine triphosphatase.	0.590
AK2	HDDC2	ENSLAFP00000004402	ENSLAFP00000001338	Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.	HD domain containing 2.	0.917
AK2	NT5E	ENSLAFP00000004402	ENSLAFP00000000205	Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.	5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.	0.894
AK2	PNP	ENSLAFP00000004402	ENSLAFP00000003122	Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.445
AK4	AK2	ENSLAFP00000006788	ENSLAFP00000004402	Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity.	Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.	0.871
AK4	ASMTL	ENSLAFP00000006788	ENSLAFP00000025438	Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity.	Acetylserotonin O-methyltransferase like.	0.730
AK4	DGUOK	ENSLAFP00000006788	ENSLAFP00000016952	Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity.	Deoxyguanosine kinase.	0.500
AK4	DTYMK	ENSLAFP00000006788	ENSLAFP00000015861	Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity.	Deoxythymidylate kinase.	0.441
AK4	HDDC2	ENSLAFP00000006788	ENSLAFP00000001338	Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity.	HD domain containing 2.	0.889
AK4	NT5E	ENSLAFP00000006788	ENSLAFP00000000205	Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity.	5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.	0.871
ASMTL	AK2	ENSLAFP00000025438	ENSLAFP00000004402	Acetylserotonin O-methyltransferase like.	Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.	0.730
ASMTL	AK4	ENSLAFP00000025438	ENSLAFP00000006788	Acetylserotonin O-methyltransferase like.	Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity.	0.730
ASMTL	DGUOK	ENSLAFP00000025438	ENSLAFP00000016952	Acetylserotonin O-methyltransferase like.	Deoxyguanosine kinase.	0.787
ASMTL	DTYMK	ENSLAFP00000025438	ENSLAFP00000015861	Acetylserotonin O-methyltransferase like.	Deoxythymidylate kinase.	0.883
ASMTL	HDDC2	ENSLAFP00000025438	ENSLAFP00000001338	Acetylserotonin O-methyltransferase like.	HD domain containing 2.	0.876
ASMTL	NT5E	ENSLAFP00000025438	ENSLAFP00000000205	Acetylserotonin O-methyltransferase like.	5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.	0.872

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