Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
GRHL3Grainyhead like transcription factor 3. (603 aa)    
Predicted Functional Partners:
TEAD3
Transcriptional enhancer factor TEF-5; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.
   
  
 0.587
ARHGAP29
Rho GTPase activating protein 29.
      
 0.584
ZNF750
Zinc finger protein 750.
   
  
 0.548
HOXB6
Homeobox B6.
    
 
 0.530
TGM1
Transglutaminase 1.
   
  
 0.525
E2F7
E2F transcription factor 7.
      
 0.521
KDF1
Keratinocyte differentiation factor 1.
   
  
 0.514
GLI3
GLI family zinc finger 3.
    
 
 0.513
IRF5
Interferon regulatory factor 5.
   
 
 0.501
IRF6
Interferon regulatory factor 6.
   
 
 0.496
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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