STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CUEDC1CUE domain containing 1. (386 aa)    
Predicted Functional Partners:
ARRDC3
Arrestin domain containing 3.
    
   0.783
TOM1
Target of myb1 membrane trafficking protein; Belongs to the TOM1 family.
    
   0.674
TOM1L2
Target of myb1 like 2 membrane trafficking protein; Belongs to the TOM1 family.
    
   0.674
ITCH
E3 ubiquitin-protein ligase.
    
   0.612
CUEDC2
CUE domain containing 2.
      
 0.600
EIF3D
Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl- tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required [...]
      
 0.574
ARRDC1
Arrestin domain containing 1.
    
   0.569
ZFPM2
Zinc finger protein, FOG family member 2.
    
 
 0.563
ARRDC4
Arrestin domain containing 4.
    
   0.523
HSPH1
Heat shock protein family H (Hsp110) member 1.
      
 0.521
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.