Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACSL3Acyl-CoA synthetase long chain family member 3. (720 aa)    
Predicted Functional Partners:
ACSL4
Acyl-CoA synthetase long chain family member 4.
   
  0.992
ACSL1
Acyl-CoA synthetase long chain family member 1.
   
 0.933
FASN
Fatty acid synthase.
  
 
 0.918
LPL
Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.
     
 0.906
ACSBG2
Acyl-CoA synthetase bubblegum family member 2.
  
0.906
ACSL5
Acyl-CoA synthetase long chain family member 5.
   
 0.905
ACSBG1
Acyl-CoA synthetase bubblegum family member 1.
  
0.901
ACSL6
AMP-binding domain-containing protein.
  
0.899
PPT2
Palmitoyl-protein thioesterase 2.
   
 
 0.898
PPT1
Palmitoyl-protein thioesterase 1.
   
 
 0.897
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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