STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMP1Matrix metallopeptidase 1. (465 aa)    
Predicted Functional Partners:
MMP9
Matrix metallopeptidase 9.
   
0.955
TIMP1
TIMP metallopeptidase inhibitor 1.
   
 0.948
MMP2
Matrix metallopeptidase 2.
   
 
0.941
MMP3
Matrix metallopeptidase 3.
  
 
0.940
TIMP2
TIMP metallopeptidase inhibitor 2.
   
 0.776
BSG
Basigin (Ok blood group).
    
 0.642
MMP7
Matrix metallopeptidase 7.
  
0.590
TIMP3
TIMP metallopeptidase inhibitor 3.
   
 0.570
TIMP4
TIMP metallopeptidase inhibitor 4.
    
 0.541
IL1B
Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.
   
 
 0.527
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.