Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPOCK3SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3. (436 aa)    
Predicted Functional Partners:
MMP14
Matrix metallopeptidase 14.
    
 0.586
TIMP2
TIMP metallopeptidase inhibitor 2.
     
  0.517
SPARC
Secreted protein acidic and cysteine rich.
   
  
 0.516
ARHGEF9
Cdc42 guanine nucleotide exchange factor 9.
   
  
 0.498
MMP16
Matrix metallopeptidase 16.
    
 0.471
MMP15
Matrix metallopeptidase 15.
    
 0.451
GH1
Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues; Belongs to the somatotropin/prolactin family.
    
 0.437
C1QL2
Complement C1q like 2.
   
  
 0.427
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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