Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPACA1Sperm acrosome associated 1. (301 aa)    
Predicted Functional Partners:
ZPBP
Zona pellucida binding protein.
   
  
 0.867
SPACA6
Uncharacterized protein.
      
 0.840
CCIN
Calicin.
   
  
 0.831
SSMEM1
Serine rich single-pass membrane protein 1.
      
 0.795
IZUMO1
Izumo sperm-egg fusion 1.
   
  
 0.790
CABS1
Calcium binding protein, spermatid associated 1.
   
  
 0.789
SPACA4
Sperm acrosome associated 4.
   
  
 0.778
SPACA9
Sperm acrosome associated 9.
      
 0.750
SPACA3
Sperm acrosome associated 3; Belongs to the glycosyl hydrolase 22 family.
   
  
 0.735
SPATA46
Spermatogenesis associated 46.
   
  
 0.689
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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