STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CDCA5Uncharacterized protein. (406 aa)    
Predicted Functional Partners:
WAPL
WAPL cohesin release factor.
    
 0.959
SMC3
Structural maintenance of chromosomes protein.
   
 0.954
CDC45
Cell division cycle 45.
   
  
 0.807
ESPL1
Extra spindle pole bodies like 1, separase.
   
 
 0.804
PDS5A
PDS5 cohesin associated factor A.
    
 0.802
PDS5B
PDS5 cohesin associated factor B.
    
 0.790
SMC1A
Structural maintenance of chromosomes protein.
   
 0.774
SMC1B
Structural maintenance of chromosomes protein.
   
 0.738
STAG1
Stromal antigen 1.
    
 0.726
PLK1
Serine/threonine-protein kinase PLK.
   
 0.713
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.