STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VPS35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (796 aa)    
Predicted Functional Partners:
VPS26A
VPS26, retromer complex component A.
   
 0.998
VPS29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
   
 0.991
VPS26B
VPS26, retromer complex component B.
   
 0.990
G3UKG6_LOXAF
Metallophos_2 domain-containing protein.
   
 0.974
SNX3
Sorting nexin 3.
   
 0.969
SNX2
Sorting nexin 2.
   
 0.966
SNX1
Sorting nexin 1.
   
 0.965
SNX12
Sorting nexin 12.
   
 0.953
DNAJC6
DnaJ heat shock protein family (Hsp40) member C6.
   
 
 0.873
SNX27
Sorting nexin 27.
    
 0.856
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.