STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CHMP6Charged multivesicular body protein 6. (200 aa)    
Predicted Functional Partners:
VPS25
Vacuolar protein sorting 25 homolog.
   
 0.997
CHMP2A
Charged multivesicular body protein 2A.
   
 0.995
VPS36
Vacuolar protein sorting 36 homolog.
 
  
 0.994
VPS4A
Uncharacterized protein; Belongs to the AAA ATPase family.
    
 0.994
SNF8
Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.
   
 0.991
VPS28
Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.
   
 0.982
VPS4B
Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family.
    
 0.980
CHMP7
Charged multivesicular body protein 7.
   
0.978
CHMP4C
Charged multivesicular body protein 4C.
   
 0.978
CHMP4B
Charged multivesicular body protein 4B.
   
 0.978
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.