NLRP2 protein (Loxodonta africana) - STRING interaction network

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NLRP2

NLR family pyrin domain containing 2. (1047 aa)

Predicted Functional Partners:

PYCARD

0.838

MAVS

0.763

IL1B

0.747

BRCC3

0.735

SUGT1

0.727

GSDMD

0.712

RELA

0.711

CARD8

0.709

TXNIP

0.707

RIPK3

0.691

Your Current Organism:

Loxodonta africana

NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRCC3	NLRP2	ENSLAFP00000011351	ENSLAFP00000001437	BRCA1/BRCA2-containing complex subunit 3.	NLR family pyrin domain containing 2.	0.735
CARD8	GSDMD	ENSLAFP00000002966	ENSLAFP00000002281	Uncharacterized protein.	Gasdermin D.	0.745
CARD8	IL1B	ENSLAFP00000002966	ENSLAFP00000003388	Uncharacterized protein.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.517
CARD8	NLRP2	ENSLAFP00000002966	ENSLAFP00000001437	Uncharacterized protein.	NLR family pyrin domain containing 2.	0.709
CARD8	PYCARD	ENSLAFP00000002966	ENSLAFP00000004815	Uncharacterized protein.	PYD and CARD domain containing.	0.684
GSDMD	CARD8	ENSLAFP00000002281	ENSLAFP00000002966	Gasdermin D.	Uncharacterized protein.	0.745
GSDMD	IL1B	ENSLAFP00000002281	ENSLAFP00000003388	Gasdermin D.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.809
GSDMD	NLRP2	ENSLAFP00000002281	ENSLAFP00000001437	Gasdermin D.	NLR family pyrin domain containing 2.	0.712
GSDMD	PYCARD	ENSLAFP00000002281	ENSLAFP00000004815	Gasdermin D.	PYD and CARD domain containing.	0.811
GSDMD	RIPK3	ENSLAFP00000002281	ENSLAFP00000010131	Gasdermin D.	Uncharacterized protein.	0.687
GSDMD	TXNIP	ENSLAFP00000002281	ENSLAFP00000009209	Gasdermin D.	Thioredoxin interacting protein.	0.403
IL1B	CARD8	ENSLAFP00000003388	ENSLAFP00000002966	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Uncharacterized protein.	0.517
IL1B	GSDMD	ENSLAFP00000003388	ENSLAFP00000002281	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Gasdermin D.	0.809
IL1B	NLRP2	ENSLAFP00000003388	ENSLAFP00000001437	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	NLR family pyrin domain containing 2.	0.747
IL1B	PYCARD	ENSLAFP00000003388	ENSLAFP00000004815	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	PYD and CARD domain containing.	0.958
IL1B	RELA	ENSLAFP00000003388	ENSLAFP00000026723	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	RELA proto-oncogene, NF-kB subunit.	0.959
IL1B	RIPK3	ENSLAFP00000003388	ENSLAFP00000010131	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Uncharacterized protein.	0.473
IL1B	TXNIP	ENSLAFP00000003388	ENSLAFP00000009209	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Thioredoxin interacting protein.	0.705
MAVS	NLRP2	ENSLAFP00000002595	ENSLAFP00000001437	Mitochondrial antiviral signaling protein.	NLR family pyrin domain containing 2.	0.763
NLRP2	BRCC3	ENSLAFP00000001437	ENSLAFP00000011351	NLR family pyrin domain containing 2.	BRCA1/BRCA2-containing complex subunit 3.	0.735

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