STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NLRP2NLR family pyrin domain containing 2. (1047 aa)    
Predicted Functional Partners:
RIPK2
Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.
   
 0.536
RNASE1
Ribonuclease A family member 1, pancreatic; Belongs to the pancreatic ribonuclease family.
    
 
 0.508
NDUFA3
NADH:ubiquinone oxidoreductase subunit A3.
      
 0.497
CDC42EP5
CDC42 effector protein 5.
      
 0.497
PYCARD
PYD and CARD domain containing.
   
 0.493
TXNIP
Thioredoxin interacting protein.
     
 0.474
TMC4
Transmembrane channel-like protein.
   
 
 0.472
LENG1
Leukocyte receptor cluster member 1.
   
  
 0.469
TTYH1
Protein tweety homolog; Probable chloride channel.
      
 0.468
TFPT
TCF3 fusion partner.
   
  
 0.459
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.