JPH2 protein (Loxodonta africana) - STRING interaction network

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JPH2

Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (685 aa)

Predicted Functional Partners:

RYR2

0.611

RABGEF1

0.538

STAC3

0.515

JPH4

0.503

RYR1

0.494

STIM1

0.486

CASQ2

0.463

CASQ1

0.463

ASB11

0.453

ASB5

0.445

Your Current Organism:

Loxodonta africana

NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASB11	JPH2	ENSLAFP00000003920	ENSLAFP00000001440	Ankyrin repeat and SOCS box containing 11.	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	0.453
ASB5	JPH2	ENSLAFP00000012283	ENSLAFP00000001440	Ankyrin repeat and SOCS box containing 5.	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	0.445
CASQ1	CASQ2	ENSLAFP00000005424	ENSLAFP00000002721	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	0.902
CASQ1	JPH2	ENSLAFP00000005424	ENSLAFP00000001440	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	0.463
CASQ1	RYR1	ENSLAFP00000005424	ENSLAFP00000026759	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Ryanodine receptor 1.	0.595
CASQ1	RYR2	ENSLAFP00000005424	ENSLAFP00000005517	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Ryanodine receptor 2.	0.942
CASQ2	CASQ1	ENSLAFP00000002721	ENSLAFP00000005424	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	0.902
CASQ2	JPH2	ENSLAFP00000002721	ENSLAFP00000001440	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	0.463
CASQ2	RYR1	ENSLAFP00000002721	ENSLAFP00000026759	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Ryanodine receptor 1.	0.595
CASQ2	RYR2	ENSLAFP00000002721	ENSLAFP00000005517	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	Ryanodine receptor 2.	0.942
JPH2	ASB11	ENSLAFP00000001440	ENSLAFP00000003920	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	Ankyrin repeat and SOCS box containing 11.	0.453
JPH2	ASB5	ENSLAFP00000001440	ENSLAFP00000012283	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	Ankyrin repeat and SOCS box containing 5.	0.445
JPH2	CASQ1	ENSLAFP00000001440	ENSLAFP00000005424	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	0.463
JPH2	CASQ2	ENSLAFP00000001440	ENSLAFP00000002721	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.	0.463
JPH2	JPH4	ENSLAFP00000001440	ENSLAFP00000020271	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	Junctophilin 4.	0.503
JPH2	RABGEF1	ENSLAFP00000001440	ENSLAFP00000005889	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	Uncharacterized protein.	0.538
JPH2	RYR1	ENSLAFP00000001440	ENSLAFP00000026759	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	Ryanodine receptor 1.	0.494
JPH2	RYR2	ENSLAFP00000001440	ENSLAFP00000005517	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	Ryanodine receptor 2.	0.611
JPH2	STAC3	ENSLAFP00000001440	ENSLAFP00000005461	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	SH3 and cysteine rich domain 3.	0.515
JPH2	STIM1	ENSLAFP00000001440	ENSLAFP00000016469	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	Stromal interaction molecule 1.	0.486

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