STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CTSWCathepsin W; Belongs to the peptidase C1 family. (376 aa)    
Predicted Functional Partners:
BCL2
BCL2 apoptosis regulator.
     
 0.902
BCL2L1
BCL2 like 1.
     
 0.902
BID
BH3-interacting domain death agonist; Counters the protective effect of Bcl-2.
   
 
 0.902
NKG7
Natural killer cell granule protein 7.
   
  
 0.738
BIRC2
Baculoviral IAP repeat containing 2.
     
 0.657
BIRC3
Baculoviral IAP repeat containing 3.
     
 0.657
BIRC5
Baculoviral IAP repeat containing 5.
     
 0.657
XIAP
X-linked inhibitor of apoptosis.
     
 0.657
PRF1
Perforin 1.
   
 0.537
GRN
Granulin precursor.
   
 0.499
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.