STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCDC85BCoiled-coil domain containing 85B. (173 aa)    
Predicted Functional Partners:
MCRS1
Microspherule protein 1.
    
 
 0.718
ZNF358
Zinc finger protein 358.
      
 0.718
GRID2IP
Grid2 interacting protein.
      
 0.638
PPP1R13B
Protein phosphatase 1 regulatory subunit 13B.
   
 
 0.628
PPP1CC
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
 
 0.572
PPP1CA
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
 
 0.572
TRIP6
Thyroid hormone receptor interactor 6.
      
 0.503
COX17
Cytochrome c oxidase copper chaperone COX17.
      
 0.494
CACNA1E
Voltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents.
      
 0.493
RPS19
Ribosomal protein S19.
      
 0.470
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.